KANSAS CITY, Mo. (AP) — Hall of Famers Reggie Jackson and Jim Rice didn’t do it. Neither did Mark McGwire, Albert Pujols, Jim Thome, Barry Bonds nor any other opposing slugger who played at Kansas City.

Carlos Santana hit five home runs in a series at spacious Kauffman Stadium, connecting for two more shots Sunday and leading the Cleveland Indians over the Royals 10-3.

Santana tied a team record for homers in a series, finishing off this four-game set with a pair of two-run shots. He has homered in three straight games, and has hit six home runs in six games.

“I know I’m hot, but I’m taking the same approach,” Santana said. “This can happen in this game when a player gets focused. It’s a help to the team.”

Santana went 3 for 3 and reached base in all five plate appearances, including drawing his major league-leading 72nd walk. The switch-hitter homered in a four-run fifth inning and hit another drive in the ninth for his fifth career multihomer game and his second of the series.

“It was pretty impressive to watch,” teammate Mike Aviles said. “Everybody knows how big he can be. He was able to drive some balls out of the park consistently from both sides.”

“Watching him all season, he has an unbelievable eye. I know his average isn’t where he wants it to be, but he got off to a slow start. But even through his struggles early in the year, he was able to find ways to get on base. You knew with a guy like him it was only a matter of time before he got back on pace.”

In his past six games, Santana is 14 for 23, including three doubles and 10 RBIs.

“He’s hot as a firecracker,” Royals manager Ned Yost said. “He’s hitting home runs right-handed. He’s hitting home runs left-handed.”

Ryan Raburn and Yan Gomes also homered for the Indians, who had lost six straight at Kauffman Stadium.

Danny Salazar (3-4) gave up three runs and seven hits over seven innings. He walked none and struck out seven.

Bruce Chen (2-3) allowed up six runs and eight hits in five-plus innings.

Nick Swisher hit an RBI single in the Indians seventh to end an 0-for-21 streak.

Billy Butler had three hits for the Royals, including an RBI double. He had homered in his previous two games, but Santana equaled Butler’s season home run total in the series.

“Santana has got a lot of pop,” Butler said. “He’s in one of those zones. A lot of guys get hot, but don’t hit four homers in a series. Five, sorry, I missed one. It just shows you how impressive it is. He’s very talented, a very strong guy.”

Santana is the first player to hit five home runs in a series since Hunter Pence for San Francisco against the Dodgers last September.

Santana tied an Indians record for most home runs in a series. The others were Hal Trosky (1934), Joe Carter (1989), Albert Belle (1995), Matt Williams (1997) and Travis Hafner (2004). Hafner did it in two-game series against the Angels.

NOTES: After missing five games with back problems, SS Asdrubal Cabrera started for the Indians. 3B Lonnie Chisenhall was held out the second straight game with a stomach virus. … Royals RHP Wade Davis has not allowed an extra-base hit this season in 44 2-3 innings. … The Indians will activate RHP Justin Masterson on Friday and start him against Texas. Masterson, a 14-game winner last year, is on the disabled list with right knee inflammation. … Chen picked Aviles off first to end the third inning. It was Chen’s 45th career pickoff, which ranks fourth among active pitchers. … Three of Raburn’s seven hits against Chen are home runs.

KANSAS CITY, Mo. (AP) — Billy Butler and the surging Kansas City Royals wrecked things for the Cleveland Indians for the second straight night.

Butler homered for the second consecutive game and the Royals overcame a five-run deficit to beat the Indians 7-5 on Saturday night for their fifth straight win.

A day after his pinch-hit, two-run homer in the eighth inning beat Cleveland, Butler connected for a tiebreaking shot in the fifth inning. It was 5-5 when he tagged Nick Hagadone for a 433-foot drive over the Royals bullpen in left field, 11 feet further than Friday’s shot.

”I’ve never been a guy that’s usually gotten distance,” Butler said. ”I caught the last two pretty good. Maybe I’m starting to figure it out and starting to put the barrel on it.

”I got a good pitch and got a good result. I’m just going to keep building off that.”

The pitch was a mistake by Hagadone.

”It was supposed to be down and away,” Hagadone said. ”It was an 0-1 fastball that was down and in the middle. He hit it pretty good. He put a good swing on it. Once he hit it I knew it was gone.”

Carlos Santana hit his third homer in two games for Cleveland, which has lost six of seven.

Jeremy Guthrie (6-9) won despite giving up five runs, 10 hits and two walks in 5 2/3 innings.

”I didn’t feel as bad as the results were in the second inning,” Guthrie said. ”I just couldn’t make a big pitch to get anybody out. They started banging around a little when I got a little tired. I really just felt frustrated. I understood the bullpen needed a rest today.

”I wasn’t certainly going to accomplish that goal as much as I wanted to after the second inning. At that point, I wanted to get as many quick outs as possible.”

Greg Holland, the fourth Kansas City reliever, got his 27th save in 29 chances.

Zach McAllister (3-6) couldn’t hold a 5-0 lead. He gave up a single to Salvador Perez to start the fifth and was replaced by Hagadone.

Guthrie had lost his previous three starts. He has an 8.44 ERA in three starts this season against the Indians.

The Indians scored five times in the second. Santana led off with a home run, and Jason Kipnis broke an 0-for-11 rut with a two-run double.

”Jeremy had a hard time stopping the bleeding in the second,” Royals manager Ned Yost said. ”But he doesn’t let much bother him. He’s very calm and very composed.”

Santana is 12 for 25 with six RBIs in his last six games.

”Right now I see the ball very well,” Santana said. ”I feel comfortable. I’m not thinking too much. I’m enjoying my time and enjoying my game.”

McAllister, just brought up from Triple-A Columbus after going 5-0 with a 2.23 ERA, faced 22 batters and 10 reached base. After starting the season 3-0, he is 0-6 in nine starts.

”When they scored those runs I just kind of fell behind,” McAllister said. ”I wasn’t able to mix when I needed to, and they were able to put the ball in play.”

Omar Infante had an RBI grounder in the third, and the Royals tied it with four more in fourth. Nori Aoki hit a two-run triple with two outs and scored on a passed ball to tie it.

NOTES: 3B Lonnie Chisenhall was scratched from the Indians lineup because of an illness. … Indians SS Asdrubal Cabrera hasn’t played since Monday because of back spasms. … Aoki batted first for the Royals after hitting in the bottom third of the order for seven games since being activated July 11 from the disabled list. He opened the season batting leadoff. … The Indians optioned RHP Josh Tomlin, who was 5-7 with a 4.47 ERA, to Triple-A Columbus. … Royals LHP Bruce Chen will make his seventh start Sunday and his third since coming off the disabled list on June 24.