HONOLULU (AP) — Health officials say a baby born in a Hawaii hospital is the first in the United States born with Zika virus.

The U.S. Centers for Disease Control and Prevention said Sunday it’s also the first infant born in the country with microcephaly  associated with Zika virus. It’s a birth defect where a baby’s head is smaller than expected. Babies with the condition often have smaller brains that might not have developed properly.

The state Department of Health announced Friday that the baby was born recently in an Oahu hospital. The mother likely had the mosquito-borne virus while living in Brazil and her newborn acquired the infection in the womb.

Neither the baby nor the mother is infectious. Officials say there’s no risk of transmission in Hawaii.

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RIO DE JANEIRO (AP) — The U.S. Centers for Disease Control says researchers have found the strongest evidence so far of a possible link between a mosquito-borne virus and a surge of birth defects.

The CDC said that researchers found the dengue-like Zika virus in the babies of two women in Brazil who miscarried and two newborns who died. Those who were born had small heads, a rare condition known as microcephaly.

CDC’s director of mosquito-borne diseases is Dr. Lyle Petersen and he says that finding the virus in brain tissue is “very significant.”

Brazil’s government says 3,530 babies have been born with microcephaly in the country since October. The number was less than 150 in 2014.